39e symposium du GRSNC
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Program

All lectures will be in English.

>>> Final program and abstracts booklet in Acrobat file format

Monday, May 8, 2017
A.M. 8h30 - 8h45 Welcome address
Richard Robitaille, GRSNC Director
Michel Bouvier, Associate Vice-Rector of Research, Discovery, Creation and Innovation
Pierrette Gaudreau, Director, Quebec Network for Research on Aging
Yves Joanette,
Lead, CIHR Dementia Research Strategy and
Chair, World Dementia Council


Introduction
Hélène Girouard, symposium co-organizer

SESSION 1
BIOMARKERS AND VASCULAR RISK FACTORS IN DEMENTIA
 
Chairperson: Lisa Marie Munter, McGill University
Learning objectives:
  • To understand the impact of vascular risk factors in the development of dementia and their role in diagnosis.
  • To learn about novel approaches for patient stratification via biomarker plasma lipidomics.
  • To learn about new animal models to study the impact of vascular risk factors on dementia.
 
A.M. 8h45 - 9h20 Steffany Bennett
Department of Biochemistry, Microbiology and Immunology,
University of Ottawa, Ottawa, ON, CANADA

Translational lipidomics: Can patients with early vascular dementia be stratified by interrogating their plasma lipidomes ?
  9h20 - 9h55 Florencia Iulita
Department of Neuroscience,
Université de Montréal, Montréal, QC, CANADA

Impact of arterial stiffness on cognitive and cerebrovascular functions.
  9h55 - 10h20 Break
  10h20 - 10h55 Donna M. Wilcock
Department of Physiology,
Sanders-Brown Center on Aging,
University of Kentucky, Lexington, KY, U.S.A.

Novel fluid biomarkers for vascular cognitive impairment.
  10h55 - 11h30 Philip A. Barber
Department of Clinical Neurosciences,
Hotchkiss Brain Institute,
University of Calgary, Calgary, AB, CANADA

Modifiable vascular risk factors and biomarkers in vascular cognitive impairment.
  11h30 - 12h00 Discussion
  12h00 - 13h00 Lunch
  13h00 - 14h00 Poster session


SESSION 2
CEREBROVASCULAR FUNCTIONS AND DEMENTIA:
BACK TO BASICS
Chairperson: Patrice Brassard, Université Laval
Learning objectives:
  • To learn about state-of-the-art methodologies to study cerebral blood flow regulation.
  • To get new knowledge about cerebrovascular functions from the pathophysiological point of view.
  • To discuss the role of exercise and diet on cognition.
 
P.M. 14h00 - 14h35 Richard Hoge
Department of Neurology and Neurosurgery,
Montreal Neurological Institute and Hospital,
McGill University, Montréal, QC, CANADA

Quantitative fMRI of the brain in healthy aging and disease.
  14h35 - 15h10 Katelyn Wood
School of Health and Exercise Science,
Centre of Heart Lung and Vascular Health,
University of British Columbia, Kelowna, BC, CANADA

Exercise to promote neural structure and function: implications for cognitive impairment.
  15h10 - 15h45 Bojana Stefanovic
Department of Medical Biophysics,
Sunnybrook Research Institute,
University of Toronto, Toronto, ON, CANADA

Two photon fluorescence microscopy of cerebrovasculature in health and Alzheimer's disease models.
  15h45 - 16h05 Break
  16h05 - 16h40 Teresa Liu-Ambrose
Department of Physical Therapy,
Vancouver Coastal Health Research Institute,
University of British Columbia, Vancouver, BC, CANADA

Exercise to promote cognitive and brain plasticity in vascular cognitive impairment.
  16h40 - 17h15 Amanda J. Kiliaan
Department of Anatomy,
Donders Institute for Brain, Cognition and Behaviour,
Radboud University, Nijmegen, THE NETHERLANDS

Effect of lipid-based diets on cerebral blood flow, brain integrity and function in mouse models for cerebrovascular disease and Alzheimer's disease.
  17h15 - 17h45 Discussion
  18h00 Cocktail and Banquet
Agora Morris et Rosalind Goodman
Pavillon Jean-Coutu
Campus de l'Université de Montréal
2940, chemin de Polytechnique


Tuesday, May 9, 2017
SESSION 3
THE CONTINUUM FROM STROKE TO ALZHEIMER'S DISEASE
 
Chairperson: Florencia Iulita, Université de Montréal
Learning objectives:
  • To discuss the influence of cerebrovascular lesions on Alzheimer's disease development.
  • To learn about the role of cerebral amyloid angiopathy as the link between stroke and Alzheimer's disease.
  • To discuss the mechanisms of neurodegeneration underlying cerebrovascular lesions.
 
A.M. 8h30 - 9h05 Vladimir Hachinski
Department of Clinical Neurological Science,
Western University, London, ON, CANADA

Cerebrovascular and Alzheimer's disease: Fellow travellers or partners in crime?
  9h05 - 9h40 Joel Ramirez
Sunnybrook Research Institute,
University of Toronto, Toronto, ON, CANADA

Small vessel disease and Alzheimer's disease: neuroimaging the twin towers of dementia.
  9h40 - 10h15 Philip B. Gorelick
Department of Translational Science & Molecular Medicine,
Mercy Health Hauenstein Neuroscience Center,
Michigan State University, Grand Rapids, MI, U.S.A

Prevention of cognitive impairment: Scientific guidance, data concordance, & windows of opportunity.
  10h15 - 10h35 Break
  10h35 - 11h10 Eric Edward Smith
Department of Clinical Neurosciences,
Hotchkiss Brain Institute,
University of Calgary, Calgary, AB, CANADA

Cerebral amyloid angiopathy: The direct link between stroke and Alzheimer's disease.
  11h10 - 11h45 Rajesh N. Kalaria
Institute of Neuroscience,
Newcastle University, Newcastle upon Tyne, UNITED KINGDOM

Vascular factors in late onset dementia and neurodegeneration.
  11h45 - 12h00 Discussion
  12h00 - 13h00 Lunch
  13h00 - 14h00 Poster session


SESSION 4
PREVENTION, REHABILITATION AND TREATMENT OF VASCULAR DEMENTIA
 
Chairperson: Hélène Girouard, Université de Montréal
Learning objectives:
  • To learn about white matter alterations and their impact on cognition.
  • To discuss strategies for prevention and treatment of vascular dementia from a clinical and pre-clinical standpoint.
  • To learn about novel disease targets for classifying patient subgroups in clinical trials.
 
P.M. 14h00 - 14h35 Edith Hamel
Department of Neurology and Neurosurgery,
Montreal Neurological Institute & Hospital,
McGill University, Montréal, QC, CANADA

White matter alterations and cognitive failure.
  14h35 - 15h10 Takashi Tarumi
Department of Neurology and Neurotherapeutics,
Institute for Exercise and Environmental Medicine,
University of Texas Southwestern Medical Center, Dallas, TX, U.S.A.

Arterial aging, cardiorespiratory fitness, and brain white matter microstructural integrity.
  15h10 - 15h45 Patrice Brassard
Department of Kinesiology,
Université Laval, Québec, QC, CANADA

Optimizing cerebrovascular adaptation through brain-targeted training strategies in patients with vascular diseases.
  15h45 - 16h05 Break
  16h05 - 16h40 JoAnne McLaurin
Department of Laboratory Medicine and Pathobiology,
Sunnybrook Research Institute,
University of Toronto, Toronto, ON, CANADA

Animal models for discovering mechanisms and synergies of VCID in mixed dementias.
  16h40 - 17h15 Gary A. Rosenberg
Department of Neurology,
University of New Mexico, Albuquerque, U.S.A.

Biomarkers for neuroinflammation in Binswanger's disease: Optimizing subgroups for clinical trials.
  17h15 - 17h45 Discussion
  17h45 - 17h55 Closing remarks

   

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